What USP 800 asks of you.
The standard spans receiving, storage, compounding, PPE, and — critically — disposal.
- Hazardous drug (HD) identification
- PPE & engineering controls
- Safe handling & compounding
- Spill response
- Trace chemo waste disposal
- RCRA-hazardous drug disposal
Identify HDs
Know which drugs on your list are hazardous under the NIOSH list referenced by USP 800.
Segregate waste
Trace chemo to yellow containers; bulk and P-listed HDs to RCRA-hazardous.
Compliant destruction
Trace chemo incinerated; RCRA-hazardous manifested to a permitted facility.
Document it
Certificate of Destruction and manifests support your HD safety program records.
Protects your staff
Correct HD waste handling is a core part of worker protection under USP 800.
Right stream, right process
Permitted destruction
Incineration and manifested hazardous disposal at permitted facilities.
Documented
Certificates and manifests archived to support audits and inspections.
What is USP 800?
USP General Chapter <800> is the standard for handling hazardous drugs in healthcare settings. It sets requirements for facilities, engineering controls, PPE, safe handling, and disposal to protect personnel, patients, and the environment from hazardous-drug exposure.
What’s the difference between USP 800 and RCRA?
USP 800 is a practice standard for safely handling hazardous drugs; RCRA is the EPA’s hazardous-waste law. They overlap at disposal: some hazardous drugs are also RCRA-hazardous waste and must be manifested and destroyed at a permitted facility.