Triune Medical Solutions
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DEA Form 41 & Form 222, explained.

A plain-English guide to DEA Form 41 (destruction of controlled substances) and DEA Form 222 (Schedule II ordering and transfer) — when each is required, how they're filed,.

What’s covered

The two forms, side by side.

Different jobs, different triggers. Mixing them up is a common audit finding.

  • Form 41 — record of controlled substances destroyed
  • Form 222 — Schedule II ordering & transfer
  • When each form is required
  • Who signs and keeps the records
  • How registrant witnesses work
How it works
1

Tell us what you have

Share the controlled substances you need destroyed or transferred, by schedule.

2

We prepare the form

Form 41 for destruction, or Form 222 for a Schedule II transfer — completed correctly.

3

Non-retrievable destruction

Controls are rendered non-retrievable to the DEA standard, witnessed and documented.

4

Records archived

Signed forms plus your Certificate of Destruction, archived and audit-ready.

DEA-registered

Forms done right

Form 41 and 222 completed to DEA requirements so your records survive an audit.

Non-retrievable standard

Destruction meets the DEA non-retrievable requirement for controlled substances.

Audit-ready records

Every form and Certificate of Destruction archived to your account.

Who we serve
Retail & chain pharmaciesHospitals & health systemsLong-term carePhysician officesSurgery centersHospice340B pharmaciesVeterinary clinics
FAQ
What is DEA Form 41 used for?

DEA Form 41 is the official Registrant Record of Controlled Substances Destroyed. A DEA registrant uses it to document controlled substances that have been destroyed — recording the drug, quantity, and method — and retains it as part of their required records.

What is DEA Form 222 used for?

DEA Form 222 is used to order and transfer Schedule II controlled substances between DEA registrants. It creates the official record of a Schedule II transaction. (Many registrants now use the electronic CSOS equivalent.)

Educational reference only, not legal advice, a formal waste determination, or training certification. Verify current federal and state requirements and the product’s safety data sheet. Waste acceptance remains subject to review by a licensed disposal partner.